An upper limit to the number of sodium channels in nerve membrane?
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منابع مشابه
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Increasing the hydrogen ion concentration of the bathing medium reversibly depresses the sodium permeability of voltage-clamped frog nerves. The depression depends on membrane voltage: changing from pH 7 to pH 5 causes a 60% reduction in sodium permeability at +20 mV, but only a 20% reduction at +180 mV. This voltage-dependent block of sodium channels by hydrogen ions is explained by assuming t...
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Sodium inactivation (SI) is the process postulated by Hodgkin and Huxley [ 11 to describe the decay of sodium permeability during a long-lasting membrane depolarization. SI underlies many physiological events, being par tially responsible for the falling phase of action potential, absolute and relative refractory states, accommodation, cathodal depression etc. (see [ l-31 for reviews). Therefor...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1967
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1967.sp008126